House: Season 5

2008
24 episodes
44m

In the Season 4 finale, after a massive bus accident left House without recollection of the accident, he and the team put the pieces of his memory together and discover Wilson’s girlfriend Amber was on the bus with him and was fatally injured. Wilson has to face the shocking realization that House was involved in Amber’s death. As Season 5 opens, with his friendship with Wilson shattered, House must determine if he’s responsible for Amber’s death and Wilson must decide if House is a destructive force in his life while Cuddy attempts to advance a reconciliation between the two of them.

Season 5 of House premiered on September 16, 2008 and has 24 episodes, from "Dying Changes Everything" to "Both Sides Now". The last episode aired on May 11, 2009.

Where to watch House

In the United States, you can stream House on Hulu, Amazon Prime Video and Philo. You can also buy it on Amazon Video, Apple TV Store, Google Play Movies and Fandango At Home. It is on streaming services in 137 countries.

Where to watch

Episodes

Episode 1Dying Changes EverythingAired September 16, 2008
In the aftermath of personal tragedy, Wilson resigns from the hospital... and from his friendship with House. Meanwhile, Thirteen struggles with her personal medical problems while helping treat an executive assistant with a similar situation to her own.
- 44m
- Directed by Deran Sarafian
- Written by Eli Attie
Guest stars
- Jamie Rose Patty Michener
- Christine Woods Lou
- Bob Sherer Patient
- Janet Song Surgeon
- David Kagen CEO
- Paul Haitkin Suit
- Bobbin Bergstrom Nurse
Episode 2Not CancerAired September 23, 2008
The team deals with an organ donor whose organs prove fatal, and the two surviving patients. Meanwhile, House hires a private detective to spy on Wilson, but hears a few things about himself that he'd rather not.
- 44m
- Directed by David Straiton
- Written by David Shore and Lawrence Kaplow
Guest stars
- Felicia Day Apple
- Tim Conlon Dr. O'Shea
- Christine McLain Emma Reed
- Jasmine Alvarez April Reed
- Michael Gaines Morgan
- Eric Kaldor Frank
- Elaine Kagan Frank's Wife
- Denice Sealy Apple's Nurse
Episode 3Adverse EventsAired September 30, 2008
A painter's undiagnosed illness affects his work, and House and his team must look at the man's paintings to determine what's wrong with him.
- 44m
- Directed by Andrew Bernstein
- Written by Dustin Paddock and Carol Green
Guest stars
- Breckin Meyer Brandon
- Marika Domińczyk Heather
- Sarah Knowlton Susan
- Drew Powell Anthony
- Liz Benoit Surgical Nurse
- Deanna Smith Female Doctor
- David Goldman Short Doctor
- Bart Tangredi Man
Episode 4BirthmarksAired October 14, 2008
While en route to his father's funeral, House must help the team with a differential diagnosis on a young Chinese girl who has collapsed under mysterious circumstances.
- 44m
- Directed by David Platt
- Written by Doris Egan and David Foster
Guest stars
- Scott Paulin Bob
- Jack Conley Sheriff Costello
- Ho-Kwan Tse Fang Dong Wen
- Raymond Ma Wu Zheng
- Samantha Quan Nicole
- Christine Healy Janice
- Jonathan Palmer Minister
- Diane Baker Blythe House
Episode 5Lucky ThirteenAired October 21, 2008
Thirteen brings her one-night stand to the hospital after the woman has a seizure. However, the woman admits she slept with Thirteen just so she could get to House and have him diagnose her condition. Meanwhile, House continues to pay Lucas to spy on Wilson.
- 44m
- Directed by Greg Yaitanes
- Written by Liz Friedman and Sara Hess
Guest stars
- Angela Gots Spencer
- Helena Barrett Woman With Thirteen
- Ali Damji Paramedic
- Michael Weston Lucas Douglas
- Bobbin Bergstrom Nurse
Episode 6JoyAired October 28, 2008
An ailing man suffers from blackouts and sleepwalks, leading the team to wonder if his sleepwalking is a symptom, or how the man is becoming exposed to something else. When the man's daughter grows ill as well, the team must provide a diagnosis before both die. Meanwhile, Cuddy adopts a newborn but when the birth mother displays a rash, she has to make a decision between putting the mother or daughter at risk.
- 44m
- Directed by Deran Sarafian
- Written by David Hoselton
Guest stars
- Salvator Xuereb Jerry Harmon
- Joanna Koulis Samantha Harmon
- Janice Allen Sadie
- Bobbin Bergstrom Nurse
- Vanessa Zima Becca
Episode 7The ItchAired November 11, 2008
The team must treat an agoraphobic who refuses to leave his house, and have to work around Cuddy, who is less than thrilled at having hospital equipment relocated. Meanwhile, House is plagued by an itch, and Cameron and Chase have relationship issues.
- 44m
- Directed by Greg Yaitanes
- Written by Peter Blake
Guest stars
- Todd Louiso Stewart Nozick
- Marcus Eley Larry Ruseckas
- Diarra Kilpatrick Sally
- Frank Noel Hal
- Kelly Michaels Guy
- Jack J. Bennett Fireman
- Yoyao Hsueh EMT
- Jim Vickers EMT
Episode 8EmancipationAired November 18, 2008
While Foreman takes on a pediatric case on his own, the rest of the team deals with a 16-year-old factory manager and emancipated minor who collapses at work. When Foreman's patient takes a turn for the worse, he's forced to question whether he can deal with the situation on his own, or if he needs House's help.
- 44m
- Directed by James Hayman
- Written by Pam Davis and Leonard Dick
Guest stars
- Nathan Gamble Evan
- Liza Colón-Zayas Maria
- Emily Rios Sophia
- Alexandra Lydon Melinda
- Kyle Red Silverstein Jona
- Bob McCracken Doug
- Al Coronel Ray
- Yolanda Rubio-Soto Sophia's Mom
Episode 9Last ResortAired November 25, 2008
A gun-wielding man from the waiting room at the Princeton-Plainsboro clinic takes House, Thirteen and several patients from the waiting room hostage in Cuddy's office. The man claims to be sick with a long undiagnosed illness and demands medical attention from the best doctor in the hospital, threatening to kill any hostages necessary along the way.
- 43m
- Directed by Katie Jacobs
- Written by Matthew V. Lewis and Eli Attie
Guest stars
- Željko Ivanek Jason
- Jack Guzman Security Guard
- Wood Harris Bowman
- Evan Jones Bill
- Natasha Gregson Wagner Sandra
- Sarah Thompson Nikki
- Evan Peters Oliver
- Marcus Chait Mitch
Episode 10Let Them Eat CakeAired December 2, 2008
The team takes on the case of a fitness guru on an all-natural diet who collapsed while filming a video. Meanwhile, Foreman conducts Huntington's Disease drug trials and Thirteen signs on as a subject, Cuddy is forced to move into House's office, and Kutner uses House's name to run an online medical-advice website.
- 44m
- Directed by Deran Sarafian
- Written by Russel Friend and Garrett Lerner
Guest stars
- Samantha Shelton Emmy
- Danielle Petty Anne Hadley
- Christopher Stapleton John Hadley
- Julia Putnam 9 Year Old Thirteen
- David Lengel Video Director
- Nicole Cannon Nurse Helen
- Bobbin Bergstrom Nurse
- Lori Petty Janice Burke
Episode 11Joy to the WorldAired December 9, 2008
House and his team deal with a bullied girl who collapses during her school's Christmas program. Meanwhile, Foreman and Thirteen grow closer during the Huntington's disease drug trials, House gives a patient a gift, the staff wonder who gave House a special gift, and Cuddy gets an unexpected gift.
- 44m
- Directed by David Straiton
- Written by Peter Blake
Guest stars
- Taylor Dooley Rachelle
- Meaghan Jette Martin Sarah
- Elizabeth Tulloch Whitney
- Sherilyn Fenn Mrs. Soellner
- B.K. Cannon Natalie
- Michael Leydon Campbell Mr. Soellner
- John Forest Geoff
- Alix Korey Anna
Episode 12PainlessAired January 19, 2009
House and the team try to diagnose a man living with severe, chronic pain; Thirteen and Foreman explore their complicated relationship; Cuddy discovers that caring for her baby leaves her with little time to run the hospital.
- 44m
- Directed by Andrew Bernstein
- Written by Thomas L. Moran and Eli Attie
Guest stars
- James Ingersoll Chris Carrick
- Aisha Kabia Nurse Rita
- Bobbin Bergstrom Nurse
- Anthony Montgomery James Carlton
- Lori Petty Janice Burke
- Sarah Danielle Madison Lynne
- Alex Fernandez Fernando
- Martin Henderson Jeff
Episode 13Big BabyAired January 26, 2009
Cuddy decides to spend more time at home to take care of her newly adopted baby and passes some of her day-to-day responsibilities off to Cameron, including supervising House. Cameron is forced to play House’s games and becomes involved in a power struggle as he and the team take on the case of a Special Education teacher who collapsed after spitting up blood in the middle of class. As House tests Cameron’s tolerance for his extreme measures, the patient continues to fall ill and House insists the teacher’s seemingly inherent goodness is actually a pathology.
- 44m
- Directed by Deran Sarafian
- Written by Lawrence Kaplow and David Foster
Guest stars
- Bobbin Bergstrom Nurse
- Erika Flores Sarah
- Andy Scott Harris Johnny
- Saige Ryan Jessica
- Tammy Dahlstrom Tammy
- Sam Gregory Screaming Kid
Episode 14The Greater GoodAired February 2, 2009
House and the team take on the case of a woman who collapsed in the middle of a cooking class, and they soon learn she is a highly-renowned cancer researcher who recently gave up her entire career in order to pursue her own personal happiness. Though the team struggles to understand how the woman could give up saving lives for the sake of her own contentment, each grapple with the pursuit of happiness (or lack thereof) in their own lives. As the patient’s condition continues to worsen, so does Thirteen’s as she begins to suffer serious and life-threatening reactions to the experimental Huntington’s Disease clinical trial. Meanwhile, Cuddy attempts to make House’s life miserable for him in retaliation for his part in her own unhappiness.
- 44m
- Directed by Lesli Linka Glatter
- Written by Sara Hess
Guest stars
- Julia Campbell Melanie
- David Purdham Chef Anthony
- Jennifer Crystal Foley Rachel Taub
- Dominic Scott Kay Jackson Smith
- Bobbin Bergstrom Nurse
- Judith Scott Dana Miller
Episode 15UnfaithfulAired February 16, 2009
When a priest who runs a homeless shelter sees a bleeding Jesus hovering at his doorstep, he is admitted to the ER. House takes on the case as a distraction for the team while he confronts Foreman and Thirteen about their relationship. The team soon learns the priest had been involved in a molestation scandal that caused him to lose his faith. However, just as they are about to dismiss his case, the patient’s condition takes a drastic turn for the worse, and House grapples with his past and his belief
- 44m
- Directed by Greg Yaitanes
- Written by David Hoselton
Guest stars
- Jimmi Simpson Daniel Bresson
- Jake Thomas Ryan
- Janet Haley Eileen
- Terrance Ellis Daryl
- Bobbin Bergstrom Nurse
Episode 16The Softer SideAired February 23, 2009
A patient with both male and female DNA has the team stumped. Meanwhile, House starts acting nicely, raising Cuddy's and Wilson's suspicions that something is terribly wrong.
- 44m
- Directed by Deran Sarafian and Greg Yaitanes
- Written by Liz Friedman
Guest stars
- Julia Campbell Melanie
- Nick Puga Ian
- Ben Reed Joseph
- Nicole Cannon Nurse Helen
- Fred Kronenberg Doctor
- Meagan Gordon Young Woman
- Dominic Scott Kay Jackson Smith
- Bobbin Bergstrom Nurse
Episode 17The Social ContractAired March 9, 2009
House and the team take on the case of Nick, a book editor who loses his inhibitions. The team realizes Nick has frontal lobe disinhibition, which causes him to speak his mind having no control over what he says and making him just like House. Meanwhile, House suspects Wilson and Taub are keeping something from him.
- 44m
- Directed by Andrew Bernstein
- Written by Doris Egan
Guest stars
- Susan Egan Audrey Greenwald
- Darcy Rose Byrnes Marika Greenwald
- Jay Karnes Nick Greenwald
- Devon Michaels Timothy Moore
- Jodi Harris Elaine
- Cyrus Deboo Dr. Kapur
- Sheri Foster Cashier
- Bobbin Bergstrom Nurse
Episode 18Here KittyAired March 16, 2009
Morgan works in a nursing home with a pet cat who only sleeps next to people if they are about to die - and does so with alarmingly accuracy. When it seems the cat has predicted her own death, Morgan, convinced she is about to die, fakes a seizure in order to get to House to have him diagnose her before it’s too late.
- 44m
- Directed by Juan José Campanella
- Written by Peter Blake
Guest stars
- Judy Greer Morgan West
- Christopher Moynihan Neil Zane
- Bob Ross Connor Allen
- Charlie Carter Billy
- Lorene Noh Business Woman
- Bobbin Bergstrom Nurse
Episode 19Locked InAired March 30, 2009
A man awakens in New York after a bicycle accident unable to move or communicate in any way. House, himself injured in a motorcycle mishap, occupies the hospital bed next to Lee and quickly annoys the doctors treating them both by insisting that Lee has “locked-in” syndrome.
- 44m
- Directed by Dan Attias
- Written by Russel Friend, Garrett Lerner and David Foster
Guest stars
- Skye Barrett Jolie
- Scotty Noyd Jr. Drake
- Yasiin Bey Lee
- John Kapelos Dr. Kurtz
- Faune Chambers Watkins Molly
- Bobbin Bergstrom Nurse
Episode 20Simple ExplanationAired April 6, 2009
Charlotte, an older woman who has spent the last six months taking care of her dying husband Eddie, is rushed to Princeton Plainsboro after collapsing from respiratory failure. The couple becomes a double mystery for the team when Eddie begins to improve as Charlotte’s condition worsens. The previously unthinkable becomes real when it seems that Charlotte will die before Eddie, and the team will be forced to make a difficult decision.
- 44m
- Directed by Greg Yaitanes
- Written by Leonard Dick
Guest stars
- Mary Jo Deschanel Julia
- Ed Brigadier Richard
- Colleen Camp Charlotte
- Meat Loaf Eddie
- Bob Rusch Phil
- Hart Boykin Arthur
- Debbie Campbell Katherine
- Taylor Hardick Rosabel
Episode 21SaviorsAired April 13, 2009
Cameron postpones her vacation with Chase in order to ask House to accept the case of an environmental radical who collapsed at a protest with unexplainable symptoms. Although suspicious of her motives, House agrees. Since she pushed him to take the case so emphatically, House forces Cameron to take the lead and run many of the tests on the patient. Meanwhile, House is unsure of Wilson’s new healthy diet.
- 44m
- Directed by Matthew Penn
- Written by Thomas L. Moran and Eli Attie
Guest stars
- Lindsey McKeon Franni
- Anne Dudek Amber Volakis
- Parisa Fakhri Susan
- Bruno Oliver Paul
- Jill Remez Sandy
- Grinnell Morris Mine Employee
- Paul Benz Mine Employee
- James McAndrew State Trooper
Episode 22House DividedAired April 27, 2009
The team takes on the case of a deaf 14-year-old named Seth who collapsed after he started “hearing” explosions while competing in a wrestling match. When the team tries to test him for seizures, Seth loses vision in one eye, complicating House’s bunk theory of “Exploding Head Syndrome.” As his condition worsens, the team has an ethical disagreement about the patient and his mother’s adamant decision to forego cochlear implants to supplement his hearing. When the prospect of giving Seth the ability to hear for the first time in his life arises, House and the team are faced with a resounding decision. Meanwhile, House’s lack of sleep starts to play tricks on his mind, but he finds his insomnia may be a gift instead of a burden
- 44m
- Directed by Greg Yaitanes
- Written by Liz Friedman and Matthew V. Lewis
Guest stars
- Clare Carey Ellie Miller
- Anne Dudek Amber Volakis
- Ryan Lane Seth Miller
- Treshelle Edmond Laura
- Becky O'Donohue Karamel
- Jorge Borrelli Deaf Coach
- Andray Johnson Referee
- Jamie Sorrentini Stripper
Episode 23Under My SkinAired May 4, 2009
House and the team take on the case of a ballerina whose lungs collapse in the middle of a performance. When the treatment causes her skin to fall off, the dancer faces not only the prospect of never dancing again but also of dying an agonizing death. The team must use their imaginations to carefully choreograph ways to test and treat her delicate body without killing her. Meanwhile, House continues to suffer from what he thinks is insomnia, and he is willing to go to desperate measures to cure it.
- 44m
- Directed by David Straiton
- Written by Pam Davis and Lawrence Kaplow
Guest stars
- Anne Dudek Amber Volakis
- Jamie Tisdale Penelope
- Charles Gevoian Maury
- Joey Gaynor Len
- Shelli Boone Molly
- Scott Dawson Ballet Master
- Pamela Shafer Company Manager
- Bobbin Bergstrom Nurse
Episode 24Both Sides NowAired May 11, 2009
House and the team are intrigued by Scott, a man whose left brain and right brain operate independently, leaving him with two distinct personalities and no control over some of his actions. As the two sides of Scott’s brain struggle for dominance, his warring personalities make it increasingly difficult for the team to figure out what is causing the unique problem. The team is forced to use some unusual methods to get him to cooperate with their necessary testing. Meanwhile, when House refuses to make an appearance in the clinic, Cuddy takes an unconventional approach to force House to make up the time with a particular patient.
- 44m
- Directed by Greg Yaitanes
- Written by Doris Egan
Guest stars
- Carl Reiner Eugene Schwartz
- Ashton Holmes Scott
- Maria Thayer Annie
- Anne Dudek Amber Volakis
- Scott Conley Warren
- Sheila Daley Paula
- Richard Sabine John
- Jason Boegh Leo